SCHEMBL28572883

SCHEMBL28572883

CCn1c2ccc(C=O)cc2c2cc(C=Cc3ccc(N(c4ccccc4)c4ccccc4)cc3)ccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 5/20 0.58
KDM4E B2RXH2 6/20 0.46
HTT P42858 3/20 0.46
POLB P06746 3/20 0.46
PKM P14618 1/20 0.46
BCHE P06276 3/20 0.45
ACHE P22303 3/20 0.45
SRC P12931 2/20 0.44
ALDH1A1 P00352 7/20 0.43
HPGD P15428 7/20 0.43
SMN1; SMN2 Q16637 5/20 0.43
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
LMNA P02545 4/20 0.43
MAPT P10636 4/20 0.43
HSD17B10 Q99714 3/20 0.42
TSHR P16473 2/20 0.42
USP2 O75604 1/20 0.42
CASP1 P29466 1/20 0.42
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29677329 1.00 PTGER4 (0.58) PTGER4KDM4EHTTPOLBPKM
SCHEMBL29677645 0.96 PTGER4 (0.54) PTGER4KDM4EHTTPOLBPKM
SCHEMBL28567473 0.96 PTGER4 (0.54) PTGER4KDM4EHTTPOLBPKM
SCHEMBL31021117 0.92 PTGER4 (0.60) PTGER4KDM4EHTTPOLBPKM
SCHEMBL28568970 0.89 PTGER4 (0.56) PTGER4KDM4EHTTPOLBPKM
SCHEMBL29677533 0.89 PTGER4 (0.56) PTGER4KDM4EHTTPOLBPKM
SCHEMBL29677444 0.86 APP (0.52) PTGER4KDM4EHTTPOLBPKM
SCHEMBL29677283 0.86 PTGER4 (0.47) PTGER4SMN1; SMN2MAPTTDP1
SCHEMBL28570847 0.86 PTGER4 (0.47) PTGER4SMN1; SMN2MAPTTDP1
SCHEMBL10123675 0.84 KDM4E (0.54) KDM4EHTTPOLBPKMBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112898799-B Carbazole organic dye and preparation method thereof, dye-sensitized titanium dioxide composite catalyst and preparation method and application thereof 江苏大学 2022-07-15 CN disclosed
CN-112898799-A Carbazole organic dye and preparation method thereof, dye-sensitized titanium dioxide composite catalyst and preparation method and application thereof 江苏大学 2021-06-04 CN disclosed