SCHEMBL31021117

SCHEMBL31021117

CCn1c2ccc(C=O)cc2c2cc(N(c3ccccc3)c3ccccc3)ccc21

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 5/20 0.60
KDM4E B2RXH2 6/20 0.48
HTT P42858 3/20 0.48
POLB P06746 2/20 0.48
PKM P14618 1/20 0.48
SRC P12931 2/20 0.46
ALDH1A1 P00352 7/20 0.45
HPGD P15428 7/20 0.45
LMNA P02545 5/20 0.45
SMN1; SMN2 Q16637 5/20 0.45
MAPT P10636 5/20 0.45
MEN1 O00255 5/20 0.45
KMT2A Q03164 5/20 0.45
HSD17B10 Q99714 3/20 0.43
TSHR P16473 2/20 0.43
USP2 O75604 1/20 0.43
CASP1 P29466 1/20 0.43
MAPK1 P28482 1/20 0.41
HBB P68871 1/20 0.41
TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29677329 0.92 PTGER4 (0.58) PTGER4KDM4EHTTPOLBPKM
SCHEMBL28572883 0.92 PTGER4 (0.58) PTGER4KDM4EHTTPOLBPKM
SCHEMBL29677533 0.91 PTGER4 (0.56) PTGER4KDM4EHTTPOLBPKM
SCHEMBL28568970 0.91 PTGER4 (0.56) PTGER4KDM4EHTTPOLBPKM
SCHEMBL28567473 0.89 PTGER4 (0.54) PTGER4KDM4EHTTPOLBPKM
SCHEMBL29677645 0.89 PTGER4 (0.54) PTGER4KDM4EHTTPOLBPKM
SCHEMBL12559419 0.87 KDM4E (0.51) PTGER4KDM4EHTTPOLBPKM
SCHEMBL21076065 0.87 KDM4E (0.51) PTGER4KDM4EHTTPOLBPKM
SCHEMBL12856895 0.87 KDM4E (0.51) PTGER4KDM4EHTTPOLBPKM
SCHEMBL22345193 0.86 PTGER4 (0.47) PTGER4KDM4EHTTPOLBPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118420518-B Benzondolium salt and preparation method and application thereof 南通大学附属医院 2025-05-09 CN disclosed
CN-118420518-A Benzondolium salt and preparation method and application thereof 南通大学附属医院 2024-08-02 CN disclosed