SCHEMBL2857299

SCHEMBL2857299

CCc1cccc2c1-c1c(c(CC)c(CC)c(CC)c1CC)[CH]2

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.36
GABRB2 P47870 4/20 0.36
ANPEP P15144 1/20 0.30
DPP4 P27487 1/20 0.30
PDK2 Q15119 1/20 0.30
KCNH2 Q12809 1/20 0.30
SCN5A Q14524 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2867421 0.80
SCHEMBL2867010 0.74 SETD7 (0.30)
SCHEMBL2870321 0.74
SCHEMBL2872291 0.73
SCHEMBL2864560 0.72
SCHEMBL8018727 0.68 PDK2 (0.42) GABRA1GABRB2ANPEPDPP4PDK2
SCHEMBL2867863 0.67 GABRA1 (0.39) GABRA1GABRB2ANPEPDPP4PDK2
SCHEMBL6234188 0.67 ELANE (0.37) GABRA1GABRB2ANPEPDPP4PDK2
SCHEMBL7110025 0.67 GABRA1 (0.35) GABRA1GABRB2
SCHEMBL245773 0.66 GABRA1 (0.57) GABRA1GABRB2PDK2KCNH2SCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1964860-B1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER TOSOH CORP (JP) 2017-07-05 EP disclosed
EP-1473323-B1 Polyethylene composition and process for producing same TOSOH CORP (JP) 2016-04-27 EP disclosed
US-7838611-B2 Ethylene polymer, catalyst for ethylene polymer production, and method for producing ethylene polymer TOSOH CORPORATION (JP) 2010-11-23 US disclosed
US-7678866-B2 Polyethylene composition and process for producing same TOSOH CORPORATION (JP) 2010-03-16 US disclosed
US-20090137755-A1 ETHYLENE POLYMER, CATALYST FOR ETHYLENE POLYMER PRODUCTION, AND METHOD FOR PRODUCING ETHYLENE POLYMER TOSOH CORPORATION (JP) 2009-05-28 US disclosed
EP-1964860-A1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER Tosoh Corporation (JP) 2008-09-03 EP disclosed
EP-1473323-A1 Polyethylene composition and process for producing same Tosoh Corporation (JP) 2004-11-03 EP disclosed
US-20040214953-A1 Polyethylene composition and process for producing same TOSOH CORPORATION 2004-10-28 US disclosed