Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28581463 | 1.00 | LMNA (0.42) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| Lithium Ion SCHEMBL30497964 | 0.93 | LMNA (0.42) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| Potassium Ion SCHEMBL30497961 | 0.93 | LMNA (0.42) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| SCHEMBL30497980 | 0.93 | LMNA (0.42) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| Lithium Ion SCHEMBL30497977 | 0.93 | — | — | |
| Potassium Ion SCHEMBL30497995 | 0.93 | — | — | |
| SCHEMBL30497974 | 0.93 | — | — | |
| Potassium Ion SCHEMBL30497960 | 0.93 | — | — | |
| SCHEMBL2178260 | 0.93 | LMNA (0.42) | LMNAALDH1A1TSHRHSD17B10MEN1 | |
| Lithium Ion SCHEMBL30497988 | 0.93 | LMNA (0.42) | LMNAALDH1A1TSHRHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602912-B | Preactivated catalyst components for the polymerization of olefins | 巴塞尔聚烯烃股份有限公司 | 2021-06-11 | — | — | CN | disclosed |