Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2827320 | 0.68 | KDM4E (0.33) | — | |
| SCHEMBL28381822 | 0.68 | KDM4E (0.33) | — | |
| SCHEMBL2515784 | 0.68 | BRD4 (0.41) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27542306 | 0.66 | SMN1; SMN2 (0.41) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28106747 | 0.63 | ALDH1A1 (0.47) | NPC1RAB9A | |
| SCHEMBL20805291 | 0.62 | NOTUM (0.39) | SMN1; SMN2 | |
| SCHEMBL5010286 | 0.61 | — | — | |
| SCHEMBL25005776 | 0.60 | ELANE (0.32) | NPC1 | |
| SCHEMBL23599024 | 0.58 | KDM4A (0.33) | SMN1; SMN2 | |
| SCHEMBL3105704 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112638376-A | Substituted tetrahydrocyclopenta [ c ] pyrroles, substituted dihydropyrrolizines, analogs thereof and methods of use thereof | 爱彼特生物制药公司 | 2021-04-09 | — | — | CN | disclosed |