Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.36 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28568645 | 0.77 | IKBKB (0.42) | GAAMAP4K4CCR1CCR5CCR8 | |
| SCHEMBL28556779 | 0.77 | MAP4K4 (0.40) | ALDH1A1LMNAHSD17B10GAAMAP4K4 | |
| SCHEMBL28559531 | 0.77 | MAP4K4 (0.40) | MAP4K4YTHDC1IKBKB | |
| Hydrochloric Acid SCHEMBL28562835 | 0.75 | MAP4K4 (0.39) | ALDH1A1LMNAHSD17B10GAAMAP4K4 | |
| Hydrochloric Acid SCHEMBL28556954 | 0.75 | MAP4K4 (0.39) | MAP4K4YTHDC1IKBKB | |
| Hydrochloric Acid SCHEMBL28562875 | 0.75 | MAP4K4 (0.39) | MAP4K4IKBKB | |
| SCHEMBL28571706 | 0.74 | MAP4K4 (0.38) | ALDH1A1HPGDHTTLMNAHSD17B10 | |
| SCHEMBL28913720 | 0.73 | MAP4K4 (0.37) | MAP4K4 | |
| SCHEMBL21355891 | 0.73 | ALDH1A1 (0.40) | ALDH1A1HPGDMAPK1HTTKDM4E | |
| SCHEMBL21355129 | 0.73 | KLKB1 (0.37) | ALDH1A1HPGDMAPK1HTTMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112135825-A | Plasma kallikrein inhibitors and uses thereof | 夏尔人类遗传性治疗公司 | 2020-12-25 | — | — | CN | disclosed |