SCHEMBL2857474

SCHEMBL2857474

CCCCCOc1cc2c3cc(OCCCCC)c(OCCCCC)cc3c3cc(OCCCCCCCCCCCCCCCCCC[Si](OC)(OC)OC)c(OCCCCC)cc3c2cc1OCCCCC

nearest known ligand 0.45

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.45
▸ SMPD1 P17405 5/20 0.43
▸ SRC P12931 1/20 0.41
▸ EGFR P00533 1/20 0.40
▸ PDE3B Q13370 1/20 0.40
▸ PDE3A Q14432 1/20 0.40
▸ TLR8 Q9NR97 2/20 0.39
▸ ENPP1 P22413 1/20 0.39
▸ CNR2 P34972 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2852344 0.97 PDE3B (0.43) LMNASMPD1SRCEGFRPDE3B
SCHEMBL2863459 0.87 CNR2 (0.38) LMNASMPD1SRCCNR2
SCHEMBL2866298 0.85 TLR8 (0.38) LMNASMPD1SRCEGFRTLR8
SCHEMBL9394813 0.84 SMPD1 (0.51) SMPD1SRCEGFRPDE3BPDE3A
SCHEMBL8974031 0.84 SMPD1 (0.51) SMPD1SRCEGFRPDE3BPDE3A
SCHEMBL9394535 0.84 SMPD1 (0.51) SMPD1SRCEGFRPDE3BPDE3A
SCHEMBL9393775 0.84 SMPD1 (0.51) SMPD1SRCEGFRPDE3BPDE3A
SCHEMBL12485172 0.84 SMPD1 (0.51) SMPD1SRCEGFRPDE3BPDE3A
SCHEMBL2866418 0.84 CNR2 (0.38) LMNASMPD1SRCCNR2
SCHEMBL8975367 0.84 NR5A1 (0.45) LMNASMPD1PDE3BPDE3ATLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7758932-B2 Liquid crystal display device and display apparatus RICOH COMPANY, LTD. (JP) 2010-07-20 — — US disclosed
US-20080305280-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY APPARATUS RICOH COMPANY, LTD. 2008-12-11 — — US disclosed
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