SCHEMBL2852344

SCHEMBL2852344

CCCCOc1cc2c3cc(OCCCC)c(OCCCC)cc3c3cc(OCCCCCCCCCCCCCCCCCC[Si](OC)(OC)OC)c(OCCCC)cc3c2cc1OCCCC

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ PDE3B Q13370 1/20 0.43
▸ PDE3A Q14432 1/20 0.43
▸ LMNA P02545 1/20 0.41
▸ SMPD1 P17405 5/20 0.40
▸ ENPP1 P22413 1/20 0.39
▸ SRC P12931 2/20 0.39
▸ EGFR P00533 2/20 0.37
▸ TLR8 Q9NR97 1/20 0.36
▸ CNR2 P34972 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2857474 0.97 LMNA (0.45) PDE3BPDE3ALMNASMPD1ENPP1
SCHEMBL2852410 0.85 PDE3B (0.36) PDE3BPDE3ASMPD1ENPP1SRC
SCHEMBL2860211 0.85 PDE3B (0.36) PDE3BPDE3ALMNACNR2
SCHEMBL2863459 0.84 CNR2 (0.38) LMNASMPD1SRCCNR2
SCHEMBL2866298 0.82 TLR8 (0.38) LMNASMPD1SRCEGFRTLR8
SCHEMBL2857308 0.82 AR (0.35) PDE3BPDE3ALMNASMPD1SRC
SCHEMBL2852415 0.81 PDE3B (0.38) PDE3BPDE3ASMPD1ENPP1EGFR
SCHEMBL2866418 0.81 CNR2 (0.38) LMNASMPD1SRCCNR2
SCHEMBL9394813 0.80 SMPD1 (0.51) PDE3BPDE3ASMPD1ENPP1SRC
SCHEMBL8974031 0.80 SMPD1 (0.51) PDE3BPDE3ASMPD1ENPP1SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7758932-B2 Liquid crystal display device and display apparatus RICOH COMPANY, LTD. (JP) 2010-07-20 — — US disclosed
US-20080305280-A1 LIQUID CRYSTAL DISPLAY DEVICE AND DISPLAY APPARATUS RICOH COMPANY, LTD. 2008-12-11 — — US disclosed
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