Benzoquinone

Benzoquinone

SCHEMBL285749

O=C1C=CC(=O)C=C1.O=C1C=CC(=O)C=C1.Oc1ccc(O)cc1

nearest known ligand 0.64

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.64
HPGD P15428 4/20 0.64
ALOX15 P16050 4/20 0.64
TDP1 Q9NUW8 3/20 0.64
CYP3A4 P08684 3/20 0.64
KDM4E B2RXH2 3/20 0.64
MEN1 O00255 2/20 0.64
NPC1 O15118 2/20 0.64
NFKB1 P19838 2/20 0.64
RAB9A P51151 2/20 0.64
KMT2A Q03164 2/20 0.64
MITF O75030 1/20 0.64
TP53 P04637 1/20 0.64
PAX8 Q06710 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
SLCO1B3 Q9NPD5 1/20 0.64
SLCO1B1 Q9Y6L6 1/20 0.64
ALDH1A1 P00352 4/20 0.57
HSD17B10 Q99714 3/20 0.57
LMNA P02545 3/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoquinone SCHEMBL51208 1.00 MAPT (0.64) MAPTHPGDALOX15TDP1CYP3A4
Benzoquinone SCHEMBL20357121 0.94 HPGD (0.58) MAPTHPGDALOX15TDP1CYP3A4
Benzoquinone SCHEMBL5695835 0.88 TDP1 (0.54) MAPTHPGDALOX15TDP1CYP3A4
Benzoquinone SCHEMBL11308712 0.88 HPGD (0.54) MAPTHPGDALOX15TDP1CYP3A4
Benzoquinone SCHEMBL1706381 0.84 TDP1 (0.65) MAPTHPGDALOX15TDP1CYP3A4
Benzoquinone SCHEMBL9140588 0.84 TDP1 (0.65) MAPTHPGDALOX15TDP1CYP3A4
Benzoquinone SCHEMBL28524671 0.84 TDP1 (0.65) MAPTHPGDALOX15TDP1CYP3A4
Benzoquinone SCHEMBL21611330 0.82 TDP1 (0.61) MAPTHPGDALOX15TDP1CYP3A4
P-Cresol SCHEMBL11878601 0.80 ACHE (0.59) MAPTHPGDALOX15TDP1CYP3A4
Aurin SCHEMBL590856 0.80 HPGD (1.00) MAPTHPGDALOX15TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100404510-C Enantioselective alkylation of tricyclic compounds SCHERING CORP (US) 2008-07-23 CN claimed
CN-116463010-B Seed coating agent with nitrogen reduction and synergy functions and application thereof 浙江大学 2024-05-17 CN disclosed
CN-116463010-A Seed coating agent with nitrogen reduction and synergy functions and application thereof 浙江大学 2023-07-21 CN disclosed
CN-113122609-B Simple and rapid colorimetric detection method for total toxicity of water body 中国科学院长春应用化学研究所 2023-06-13 CN disclosed
CN-108352413-B Method for manufacturing double-sided battery 索拉昂德有限公司 2021-11-02 CN disclosed
CN-106591103-B System and method for efficient electronic sequencing and detection 吉纳普赛斯股份有限公司 2021-06-04 CN disclosed
CN-112414980-A Optical chemical sensor, sensor cover, use of an optical chemical sensor and method for producing an analyte-sensitive layer of an optical chemical sensor 恩德莱斯和豪瑟尔分析仪表两合公司 2021-02-26 CN disclosed
CN-107188799-B Fenbufen eutectic crystal and preparation method and application thereof 中国食品药品检定研究院 2020-10-30 CN disclosed
WO-2020021252-A1 COMPOUNDS FOR TREATING INFECTIONS CAUSED BY RIFAMPICIN-RESISTANT BACTERIA DEMURIS LTD (GB) 2020-01-30 WO disclosed
CN-110088233-A Effective curing agent of free-radical crosslinkable polymers 阿科玛股份有限公司 2019-08-02 CN disclosed
US-20120091008-A1 PH MEASUREMENT DEVICE MEDERMICA LIMITED (GB) 2012-04-19 US disclosed
EP-2427757-A2 PH MEASUREMENT DEVICE Medermica Limited (GB) 2012-03-14 EP disclosed
WO-2010128280-A2 PH MEASUREMENT DEVICE MEDERMICA LIMITED (GB) 2010-11-11 WO disclosed
CN-101544604-A Tricyclic compounds SCHERING CORP (US) 2009-09-30 CN disclosed
CN-100503597-C Enantioselective alkylation of tricyclic compounds SCHERING CORP (US) 2009-06-24 CN disclosed
CN-1717392-A Enantioselective alkylation of tricyclic compounds SCHERING CORP (US) 2006-01-04 CN disclosed