Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | TXN | P10599 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333399 | 0.86 | PDE5A (0.41) | PDE5AHTR2CLMNAMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5372075 | 0.85 | PDE5A (0.40) | PDE5AHTR2CLMNAMEN1ALDH1A1 | |
| SCHEMBL5435892 | 0.79 | PDE5A (0.40) | PDE5ALMNAMEN1ALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL5328910 | 0.78 | PDE5A (0.38) | PDE5ALMNAMEN1KMT2AHDAC1 | |
| Hydrochloric Acid SCHEMBL5364779 | 0.77 | BRD4 (0.41) | PDE5AHDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL5324056 | 0.77 | BCL6 (0.44) | PDE5ALMNAMEN1KMT2AHDAC1 | |
| SCHEMBL4038080 | 0.76 | CCNA2 (0.47) | PDE5AMEN1ALDH1A1HPGDPDE1A | |
| SCHEMBL4036183 | 0.76 | PDE5A (0.39) | PDE5ALMNAMEN1ALDH1A1HPGD | |
| SCHEMBL4040447 | 0.76 | PDE5A (0.41) | PDE5AMEN1ALDH1A1HPGDPDE1A | |
| SCHEMBL4037512 | 0.76 | PDE5A (0.38) | PDE5AMEN1ALDH1A1HPGDPDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |