Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | KDM4D | Q6B0I6 | 5/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28578378 | 0.87 | F10 (0.37) | DRD2DPP4EPHX1RENMAPK8 | |
| SCHEMBL28575236 | 0.85 | DRD2 (0.44) | DRD2DPP4CTSSCTSKKDM4D | |
| SCHEMBL28575235 | 0.85 | DRD2 (0.44) | DRD2DPP4CTSSCTSKKDM4D | |
| SCHEMBL28588250 | 0.82 | DRD2 (0.42) | DRD2DPP4CTSSCTSKKDM4D | |
| SCHEMBL28588251 | 0.82 | DRD2 (0.42) | DRD2DPP4CTSSCTSKKDM4D | |
| SCHEMBL21822134 | 0.82 | DRD2 (0.42) | DRD2DPP4CTSSCTSKKDM4D | |
| SCHEMBL25017654 | 0.82 | DRD2 (0.40) | DRD2DPP4DRD3XIAP | |
| SCHEMBL28580762 | 0.81 | DRD2 (0.40) | DRD2DPP4CTSSCTSKKDM4D | |
| SCHEMBL28580759 | 0.81 | DRD2 (0.40) | DRD2DPP4CTSSCTSKKDM4D | |
| SCHEMBL30180715 | 0.81 | DRD2 (0.40) | DRD2DPP4CTSSCTSKKDM4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |