SCHEMBL2857526

SCHEMBL2857526

CC1=C(C)C([Zr](Cl)(Cl)(=C(c2ccccc2)c2ccccc2)C2c3ccccc3-c3ccccc32)c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
KMT2A Q03164 1/20 0.31
SLC22A2 O15244 1/20 0.30
SLC22A3 O75751 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2863579 0.91 MEN1 (0.32) MEN1LMNAKMT2A
SCHEMBL2862555 0.88 NPC1 (0.33) LMNA
SCHEMBL6909725 0.87 SLC22A2 (0.33) MEN1LMNAKMT2ASLC22A2SLC22A3
SCHEMBL2855722 0.87 NPC1 (0.33) LMNA
SCHEMBL2868435 0.79 LMNA (0.32) MEN1LMNAKMT2A
SCHEMBL2861168 0.77
SCHEMBL21986499 0.76
SCHEMBL2870987 0.76 HSP90AA1 (0.31)
SCHEMBL22607472 0.75
SCHEMBL2867541 0.75 PDCD1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1964860-B1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER TOSOH CORP (JP) 2017-07-05 EP disclosed
EP-1473323-B1 Polyethylene composition and process for producing same TOSOH CORP (JP) 2016-04-27 EP disclosed
US-7838611-B2 Ethylene polymer, catalyst for ethylene polymer production, and method for producing ethylene polymer TOSOH CORPORATION (JP) 2010-11-23 US disclosed
US-7678866-B2 Polyethylene composition and process for producing same TOSOH CORPORATION (JP) 2010-03-16 US disclosed
US-20090137755-A1 ETHYLENE POLYMER, CATALYST FOR ETHYLENE POLYMER PRODUCTION, AND METHOD FOR PRODUCING ETHYLENE POLYMER TOSOH CORPORATION (JP) 2009-05-28 US disclosed
US-20040214953-A1 Polyethylene composition and process for producing same TOSOH CORPORATION 2004-10-28 US disclosed