Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | GPR174 | Q9BXC1 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4300344 | 0.90 | PDGFRB (0.45) | MAPTALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL5150299 | 0.88 | MAPT (0.45) | MAPTALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL4280091 | 0.85 | MAPT (0.43) | MAPTALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL4280859 | 0.84 | MAPT (0.40) | MAPTALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL31053309 | 0.82 | HCAR2 (0.40) | MAPTALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL29150029 | 0.79 | KMT2A (0.39) | MAPTALDH1A1SMN1; SMN2KMT2AKDM4E | |
| SCHEMBL4277099 | 0.78 | MAPT (0.44) | MAPTALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL28654992 | 0.78 | ALDH1A1 (0.50) | MAPTALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL4281268 | 0.76 | MAPT (0.40) | MAPTALDH1A1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL28965649 | 0.76 | PDGFRB (0.64) | MAPTALDH1A1SMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112824398-B | Immunomodulator | 成都先导药物开发股份有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-112824398-A | Immunomodulator | 成都先导药物开发股份有限公司 | 2021-05-21 | — | — | CN | disclosed |