Biphenyl

Biphenyl

SCHEMBL28575404

COC(=O)c1ccccc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.86
PTPN1 P18031 1/20 0.66
EGFR P00533 1/20 0.64
RAB9A P51151 6/20 0.60
MAPT P10636 3/20 0.60
L3MBTL1 Q9Y468 2/20 0.60
CASP3 P42574 1/20 0.60
SENP8 Q96LD8 1/20 0.60
SENP7 Q9BQF6 1/20 0.60
SENP6 Q9GZR1 1/20 0.60
SLC6A3 Q01959 1/20 0.56
F2 P00734 1/20 0.56
LMNA P02545 1/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
NPC1 O15118 3/20 0.56
ALDH1A1 P00352 3/20 0.56
HPGD P15428 2/20 0.56
AGTR1 P30556 1/20 0.56
CA1 P00915 3/20 0.56
CA2 P00918 3/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1105491 0.93 TSHR (0.75) TSHRPTPN1EGFRRAB9AMAPT
Methyl Benzoate SCHEMBL28945661 0.93 TSHR (1.00) TSHRPTPN1RAB9AMAPTL3MBTL1
Methyl Benzoate SCHEMBL29105567 0.93 TSHR (1.00) TSHRPTPN1RAB9AMAPTL3MBTL1
Methyl Benzoate SCHEMBL29831725 0.93 TSHR (1.00) TSHRPTPN1RAB9AMAPTL3MBTL1
Methyl Benzoate SCHEMBL1867855 0.93 TSHR (1.00) TSHRPTPN1RAB9AMAPTL3MBTL1
Methyl Benzoate SCHEMBL28537345 0.93 TSHR (1.00) TSHRPTPN1RAB9AMAPTL3MBTL1
Methyl Benzoate SCHEMBL29039896 0.93 TSHR (1.00) TSHRPTPN1RAB9AMAPTL3MBTL1
Methyl Benzoate SCHEMBL1332323 0.93 TSHR (1.00) TSHRPTPN1RAB9AMAPTL3MBTL1
Methyl Benzoate SCHEMBL7200 0.93 TSHR (1.00) TSHRPTPN1RAB9AMAPTL3MBTL1
Methyl Benzoate SCHEMBL7005079 0.91 TSHR (0.95) TSHRPTPN1RAB9AMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116063153-B Synthesis method of 4-diphenyl methanol 中国科学院大连化学物理研究所 2025-03-14 CN claimed
CN-116063153-A Synthesis method of 4-diphenyl methanol 中国科学院大连化学物理研究所 2023-05-05 CN claimed
CN-112876355-B Method for preparing carboxylic ester compound by breaking carbon-carbon bond through oxidation of secondary alcohol compound 中国科学院大连化学物理研究所 2022-03-08 CN disclosed
CN-112876355-A Method for preparing carboxylic ester compound by breaking carbon-carbon bond through oxidation of secondary alcohol compound 中国科学院大连化学物理研究所 2021-06-01 CN disclosed