SCHEMBL28575411

SCHEMBL28575411

OB(O)c1c(-c2cccc3ccccc23)ccc2cc3ccccc3cc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.42
HSD17B10 Q99714 4/20 0.42
HIF1A Q16665 2/20 0.42
CYP1B1 Q16678 1/20 0.42
GPR84 Q9NQS5 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
HPGD P15428 3/20 0.38
CYP1A2 P05177 2/20 0.38
KDM4E B2RXH2 4/20 0.37
GAA P10253 3/20 0.37
SOS1 Q07889 1/20 0.36
AKR1C3 P42330 1/20 0.36
AKR1C2 P52895 1/20 0.36
TSHR P16473 2/20 0.36
ERBB2 P04626 1/20 0.36
FYN P06241 1/20 0.36
MAOA P21397 1/20 0.36
ACHE P22303 1/20 0.36
AHR P35869 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2510601 0.88 ALDH1A1 (0.41) ALDH1A1HSD17B10HIF1ACYP1B1GPR84
SCHEMBL28558636 0.80 MEN1 (0.43) ALDH1A1HSD17B10HIF1ACYP1B1GPR84
SCHEMBL440879 0.78 ALDH1A1 (0.54) ALDH1A1HSD17B10HIF1ACYP1B1GPR84
SCHEMBL29593313 0.78 ALDH1A1 (0.54) ALDH1A1HSD17B10HIF1ACYP1B1GPR84
SCHEMBL4397710 0.78 ALDH1A1 (0.47) ALDH1A1HSD17B10HIF1ACYP1B1CA1
SCHEMBL10276976 0.77 ALDH1A1 (0.52) ALDH1A1HSD17B10HIF1ACYP1B1GPR84
SCHEMBL30919444 0.77 ALDH1A1 (0.52) ALDH1A1HSD17B10HIF1ACYP1B1GPR84
SCHEMBL27737859 0.77 ALDH1A1 (0.52) ALDH1A1HSD17B10HIF1ACYP1B1GPR84
SCHEMBL19547599 0.76 ALDH1A1 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1GPR84
Anthracene SCHEMBL4659489 0.76 ALDH1A1 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110376320-B Method for full-automatic series solid-phase extraction of brassinosteroids in plants 中国科学院大连化学物理研究所 2021-04-27 CN claimed
CN-110376320-B Method for full-automatic series solid-phase extraction of brassinosteroids in plants 中国科学院大连化学物理研究所 2021-04-27 CN disclosed