Acetone

Acetone

SCHEMBL28575425

CC(C)=O.O=C(O)c1ccco1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.60
CES1 P23141 1/20 0.60
PTPN1 P18031 1/20 0.59
POLB P06746 4/20 0.52
KMT2A Q03164 3/20 0.52
TDP1 Q9NUW8 2/20 0.52
MEN1 O00255 2/20 0.52
ALDH1A1 P00352 2/20 0.52
THRB P10828 1/20 0.52
APEX1 P27695 1/20 0.52
RECQL P46063 1/20 0.52
PTGS1 P23219 1/20 0.51
RAB9A P51151 4/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
TP53 P04637 1/20 0.50
GAA P10253 1/20 0.50
ERCC5 P28715 1/20 0.50
FEN1 P39748 1/20 0.50
AGTR1 P30556 2/20 0.47
NPC1 O15118 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL584512 0.95 CES2 (0.60) CES2CES1PTPN1POLBKMT2A
Methyl Alcohol SCHEMBL11566008 0.93 CES2 (0.62) CES2CES1PTPN1POLBKMT2A
SCHEMBL24446 0.93
SCHEMBL3811314 0.93 CES2 (0.68) CES2CES1PTPN1POLBKMT2A
Acetamide SCHEMBL4667041 0.91 PTGS1 (0.57) CES2CES1PTPN1POLBKMT2A
SCHEMBL28143240 0.91 CES2 (0.56) CES2CES1PTPN1POLBKMT2A
SCHEMBL6129939 0.91 CES2 (0.60) CES2CES1PTPN1POLBKMT2A
Methylamine SCHEMBL27782227 0.91 CES2 (0.60) CES2CES1PTPN1POLBKMT2A
SCHEMBL25196785 0.91
Water SCHEMBL728285 0.91

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112694476-B Furan formamido beta-carboline compound and preparation method and application thereof 浙江工业大学 2022-03-18 CN claimed
CN-112694476-A Furan formamido beta-carboline compound and preparation method and application thereof 浙江工业大学 2021-04-23 CN claimed
CN-112694476-A Furan formamido beta-carboline compound and preparation method and application thereof 浙江工业大学 2021-04-23 CN disclosed