Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1098262 | 0.86 | LMNA (0.34) | MAPK1LMNATP53NFKB1CYP2C19 | |
| SCHEMBL16390469 | 0.78 | GMNN (0.34) | MAPK1LMNATP53NFKB1CYP2C19 | |
| SCHEMBL2786355 | 0.75 | KDM4E (0.30) | LMNATP53NFKB1THPOGMNN | |
| SCHEMBL435252 | 0.71 | MAPK1 (0.36) | MAPK1LMNATP53NFKB1CYP2C19 | |
| SCHEMBL4458616 | 0.69 | — | — | |
| SCHEMBL5706333 | 0.68 | — | — | |
| SCHEMBL15484210 | 0.68 | — | — | |
| SCHEMBL28884762 | 0.68 | PPM1B (0.40) | LMNATP53NFKB1THPOGMNN | |
| SCHEMBL28644478 | 0.67 | LMNA (0.37) | MAPK1LMNATP53NFKB1CYP2C19 | |
| Bicarbonate SCHEMBL8469106 | 0.67 | LMNA (0.34) | MAPK1LMNATP53NFKB1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112105671-A | Cycloaliphatic amines used in epoxy formulations: novel curing agents for epoxy systems | 赢创运营有限公司 | 2020-12-18 | — | — | CN | claimed |