Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2872472 | 0.88 | — | — | |
| Hydrochloric Acid SCHEMBL2867898 | 0.87 | MEN1 (0.32) | MEN1NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL2862535 | 0.86 | NPC1 (0.34) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2872423 | 0.86 | NPC1 (0.32) | NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL2871022 | 0.82 | MEN1 (0.32) | MEN1NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL2863292 | 0.82 | MEN1 (0.32) | MEN1NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL2861627 | 0.82 | NPC1 (0.32) | MEN1NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL2862740 | 0.81 | CNR2 (0.32) | CNR2MEN1NPC1TP53RAB9A | |
| Hydrochloric Acid SCHEMBL2870400 | 0.80 | PPIA (0.34) | MEN1NPC1RAB9AKMT2A | |
| Hydrochloric Acid SCHEMBL15815286 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7838611-B2 | Ethylene polymer, catalyst for ethylene polymer production, and method for producing ethylene polymer | TOSOH CORPORATION (JP) | 2010-11-23 | — | — | US | disclosed |
| US-7678866-B2 | Polyethylene composition and process for producing same | TOSOH CORPORATION (JP) | 2010-03-16 | — | — | US | disclosed |
| US-20090137755-A1 | ETHYLENE POLYMER, CATALYST FOR ETHYLENE POLYMER PRODUCTION, AND METHOD FOR PRODUCING ETHYLENE POLYMER | TOSOH CORPORATION (JP) | 2009-05-28 | — | — | US | disclosed |
| US-20040214953-A1 | Polyethylene composition and process for producing same | TOSOH CORPORATION | 2004-10-28 | — | — | US | disclosed |