⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459159 | 0.86 | — | — | |
| SCHEMBL28691544 | 0.70 | — | — | |
| SCHEMBL6990535 | 0.69 | — | — | |
| SCHEMBL2497267 | 0.67 | — | — | |
| SCHEMBL743262 | 0.67 | — | — | |
| SCHEMBL14974813 | 0.64 | — | — | |
| SCHEMBL30040317 | 0.64 | — | — | |
| Methylamine SCHEMBL8761530 | 0.63 | — | — | |
| SCHEMBL7511961 | 0.63 | — | — | |
| SCHEMBL31460361 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113387931-A | Compound capable of inhibiting or degrading protein kinase, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2021-09-14 | — | — | CN | claimed |
| CN-112812100-A | Compound capable of degrading BTK kinase, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2021-05-18 | — | — | CN | claimed |
| CN-112812100-B | Compound capable of degrading BTK kinase, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2022-04-05 | — | — | CN | disclosed |
| CN-113387931-A | Compound capable of inhibiting or degrading protein kinase, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2021-09-14 | — | — | CN | disclosed |
| CN-112812100-A | Compound capable of degrading BTK kinase, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-112010858-A | BTK inhibitor, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2020-12-01 | — | — | CN | disclosed |