⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28575960 | 0.86 | — | — | |
| SCHEMBL28691544 | 0.77 | — | — | |
| SCHEMBL7511961 | 0.70 | — | — | |
| SCHEMBL28161609 | 0.66 | — | — | |
| SCHEMBL28279806 | 0.66 | — | — | |
| SCHEMBL31460361 | 0.65 | — | — | |
| SCHEMBL312465 | 0.64 | — | — | |
| SCHEMBL28399280 | 0.64 | — | — | |
| SCHEMBL12466449 | 0.61 | — | — | |
| SCHEMBL18339634 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108290055-B | Oxime compounds as agonists of the muscle M1 and/or M4 receptor | 赫普泰雅治疗有限公司 | 2021-05-14 | — | — | CN | claimed |
| CN-108371660-B | Application of tetrahydrocyclopentapyrrole compound and derivative thereof | 五邑大学 | 2020-03-10 | — | — | CN | claimed |
| EP-0680972-B1 | Trifluoromethylketone peptide derivatives, process for their preparation and pharmaceutical compositions comprising them | ADIR (FR) | 2000-03-08 | — | — | EP | claimed |
| US-5567804-A | HUMAN LEUCOCYTE ELASTASE INHIBITOR; ANTIOXIDANT | ADIR ET COMPAGNIE (FR) | 1996-10-22 | — | — | US | claimed |
| US-5565429-A | HUMAN LEUCOCYTE ELASTASE INHIBITORS; EMPHYSEMA; ANTIARTHRITIC AGENTS; RHEUMATIC DISEASES | ADIR ET COMPAGNIE (FR) | 1996-10-15 | — | — | US | claimed |
| EP-0680972-A1 | Trifluoromethylketone peptide derivatives, process for their preparation and pharmaceutical compositions comprising them | ADIR ET COMPAGNIE (FR) | 1995-11-08 | — | — | EP | claimed |
| US-5190923-A | For treatment of neurological disorders such as cognitive disorders | ADIR ET COMPAGNIE (FR) | 1993-03-02 | — | — | US | claimed |
| CN-118518439-A | Ionic liquid preparation, tissue treatment method and application thereof | 清华大学 | 2024-08-20 | — | — | CN | disclosed |
| CN-110944992-B | Pharmaceutical compounds | 赫普泰雅治疗有限公司 | 2023-05-16 | — | — | CN | disclosed |
| US-20230014137-A1 | COMPOUND HAVING LYSOPHOSPHATIDIC ACID RECEPTOR AGONIST ACTIVITY AND PHARMACEUTICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2023-01-19 | — | — | US | disclosed |
| EP-4066895-A1 | COMPOUND HAVING LYSOPHOSPHATIDIC ACID RECEPTOR AGONISTIC ACTIVITY AND PHARMACEUTICAL USE OF SAID COMPOUND | ONO Pharmaceutical Co., Ltd. (JP) | 2022-10-05 | — | — | EP | disclosed |
| WO-2021107125-A1 | COMPOUND HAVING LYSOPHOSPHATIDIC ACID RECEPTOR AGONISTIC ACTIVITY AND PHARMACEUTICAL USE OF SAID COMPOUND | 小野薬品工業株式会社 | 2021-06-03 | — | — | WO | disclosed |
| CN-108290055-B | Oxime compounds as agonists of the muscle M1 and/or M4 receptor | 赫普泰雅治疗有限公司 | 2021-05-14 | — | — | CN | disclosed |
| EP-0912602-A1 | METHOD OF TREATING BETA-AMYLOID PEPTIDE ASSOCIATED CONDITIONS USING TRH | ELI LILLY AND COMPANY (US) | 1999-05-06 | — | — | EP | disclosed |
| WO-1997028184-A1 | METHOD OF TREATING BETA-AMYLOID PEPTIDE ASSOCIATED CONDITIONS USING TRH | ELI LILLY AND COMPANY (US) | 1997-08-07 | — | — | WO | disclosed |
| US-5567804-A | HUMAN LEUCOCYTE ELASTASE INHIBITOR; ANTIOXIDANT | ADIR ET COMPAGNIE (FR) | 1996-10-22 | — | — | US | disclosed |
| US-5565429-A | HUMAN LEUCOCYTE ELASTASE INHIBITORS; EMPHYSEMA; ANTIARTHRITIC AGENTS; RHEUMATIC DISEASES | ADIR ET COMPAGNIE (FR) | 1996-10-15 | — | — | US | disclosed |
| EP-0680972-A1 | Trifluoromethylketone peptide derivatives, process for their preparation and pharmaceutical compositions comprising them | ADIR ET COMPAGNIE (FR) | 1995-11-08 | — | — | EP | disclosed |
| EP-0680972-A1 | Trifluoromethylketone peptide derivatives, process for their preparation and pharmaceutical compositions comprising them | ADIR ET COMPAGNIE (FR) | 1995-11-08 | — | — | EP | disclosed |
| US-5190923-A | For treatment of neurological disorders such as cognitive disorders | ADIR ET COMPAGNIE (FR) | 1993-03-02 | — | — | US | disclosed |