Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16989324 | 0.83 | CA1 (0.65) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL16989326 | 0.83 | CA1 (0.65) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL60621 | 0.81 | CA1 (0.67) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL30372446 | 0.80 | CA1 (0.61) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL1045608 | 0.79 | NFE2L2 (0.64) | MAPTNFE2L2KDM4EHSD17B10CYP1A1 | |
| SCHEMBL1045609 | 0.79 | NFE2L2 (0.64) | MAPTNFE2L2KDM4EHSD17B10CYP1A1 | |
| SCHEMBL4014094 | 0.79 | CA1 (0.59) | CA1CA2MEN1KMT2AMAPT | |
| Cassiferaldehyde SCHEMBL28269438 | 0.79 | CA1 (0.69) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL16952390 | 0.79 | CA1 (0.69) | CA1CA2MEN1KMT2AMAPT | |
| SCHEMBL9112041 | 0.78 | NFE2L2 (0.41) | CA1CA2MAPTALDH1A1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109134294-B | Cis-double-bond amide compound and preparation method and application thereof | 海南师范大学 | 2021-06-04 | — | — | CN | disclosed |