Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.60 |
| ▸ | FEN1 | P39748 | 1/20 | 0.60 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 5/20 | 0.57 |
| ▸ | GLA | P06280 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | RAF1 | P04049 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28916010 | 0.93 | ERCC1 (0.64) | ERCC1FEN1ERCC4KDM4EALDH1A1 | |
| SCHEMBL28582957 | 0.93 | ERCC1 (0.68) | ERCC1FEN1ERCC4KDM4EALDH1A1 | |
| SCHEMBL28574815 | 0.88 | ERCC1 (0.59) | ERCC1FEN1ERCC4KDM4EALDH1A1 | |
| SCHEMBL28574819 | 0.88 | MAPT (0.62) | ERCC1FEN1ERCC4KDM4EALDH1A1 | |
| SCHEMBL28583430 | 0.88 | ERCC1 (0.59) | ERCC1FEN1ERCC4KDM4EALDH1A1 | |
| SCHEMBL28574062 | 0.88 | ERCC1 (0.59) | ERCC1FEN1ERCC4KDM4EALDH1A1 | |
| SCHEMBL28574853 | 0.87 | ERCC1 (0.57) | ERCC1FEN1ERCC4KDM4EALDH1A1 | |
| SCHEMBL7978027 | 0.86 | KDM4E (0.67) | ERCC1FEN1ERCC4KDM4EALDH1A1 | |
| SCHEMBL28594072 | 0.86 | ERCC1 (0.56) | ERCC1FEN1ERCC4KDM4EALDH1A1 | |
| SCHEMBL28576642 | 0.85 | ERCC1 (0.55) | ERCC1FEN1ERCC4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112759551-B | 2, 5-substituent 1H-imidazole-4-carboxylate compound and synthetic purification method thereof | 宝鸡文理学院 | 2023-10-27 | — | — | CN | disclosed |
| CN-112759551-A | 2, 5-substituent 1H-imidazole-4-carboxylic ester compound and synthesis and purification method thereof | 宝鸡文理学院 | 2021-05-07 | — | — | CN | disclosed |