Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | GLA | P06280 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | PIN1 | Q13526 | 5/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.54 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.54 |
| ▸ | FEN1 | P39748 | 1/20 | 0.54 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.54 |
| ▸ | DHODH | Q02127 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29093221 | 0.91 | PIN1 (0.69) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL7992039 | 0.88 | MAPK14 (0.56) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL7977738 | 0.88 | MAPK14 (0.56) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL7977763 | 0.88 | CTRC (0.53) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL7977705 | 0.86 | DHODH (0.54) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL28576641 | 0.86 | ERCC1 (0.60) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL7988191 | 0.85 | NPBWR1 (0.53) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL7989975 | 0.84 | DHODH (0.61) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL7977380 | 0.84 | MEN1 (0.56) | KDM4EALDH1A1GLAGAAHPGD | |
| SCHEMBL7992089 | 0.83 | MAPK14 (0.62) | PIN1CYP1A2CYP2C19MAPK1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |