Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 9/20 | 0.59 |
| ▸ | INSR | P06213 | 10/20 | 0.58 |
| ▸ | IGF1R | P08069 | 10/20 | 0.58 |
| ▸ | ALK | Q9UM73 | 10/20 | 0.58 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26717249 | 0.82 | INSR (0.72) | MAP4K1INSRIGF1RALKEGFR | |
| SCHEMBL28564190 | 0.79 | EGFR (0.64) | MAP4K1INSRIGF1RALKEGFR | |
| SCHEMBL21557830 | 0.78 | ALK (0.81) | MAP4K1INSRIGF1RALKEGFR | |
| SCHEMBL28587037 | 0.78 | PTK2 (0.56) | MAP4K1INSRIGF1RALKEGFR | |
| SCHEMBL28996875 | 0.78 | MAP4K1 (0.58) | MAP4K1INSRIGF1RALKEGFR | |
| SCHEMBL29833023 | 0.77 | INSR (0.59) | MAP4K1INSRIGF1RALKEGFR | |
| SCHEMBL28569396 | 0.77 | ALK (0.64) | MAP4K1INSRIGF1RALKEGFR | |
| SCHEMBL4531370 | 0.76 | LRRK2 (0.58) | INSRALK | |
| SCHEMBL31229842 | 0.76 | ALK (0.62) | MAP4K1INSRIGF1RALKEGFR | |
| SCHEMBL11916544 | 0.76 | ALK (0.78) | MAP4K1INSRIGF1RALKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112771032-A | Pyrimidine pyrazole compounds as fourth generation EGFR inhibitors | 江苏先声药业有限公司 | 2021-05-07 | — | — | CN | disclosed |