SCHEMBL28577183

SCHEMBL28577183

CP(=O)(Oc1ccc(S)cc1)Oc1ccc(S)cc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.43
TSHR P16473 1/20 0.43
CYP2C19 P33261 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
BLM P54132 1/20 0.34
HPGD P15428 2/20 0.34
SRC P12931 1/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PKM P14618 2/20 0.32
HTT P42858 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL776644 0.78 TSHR (0.70) CYP3A4TSHRMEN1KMT2AHPGD
SCHEMBL7207078 0.76 SRC (0.60) CYP3A4TSHRCYP2C19SMN1; SMN2MEN1
SCHEMBL11177722 0.76 MEN1 (0.61) CYP3A4TSHRCYP2C19SMN1; SMN2MEN1
SCHEMBL4140665 0.76 HPGD (0.55) CYP3A4TSHRCYP2C19SMN1; SMN2MEN1
SCHEMBL13056457 0.76 TDP1 (0.48) CYP3A4TSHRCYP2C19SMN1; SMN2MEN1
SCHEMBL310184 0.75 SRC (0.58) MEN1KMT2AHPGDSRCLMNA
SCHEMBL28572424 0.74 SRC (0.37) CYP2C19HPGDSRCLMNACYP1A2
Hydrochloric Acid SCHEMBL29186320 0.73 SRC (0.56) MEN1KMT2AHPGDSRCLMNA
SCHEMBL778838 0.73 SMN1; SMN2 (0.69) CYP3A4TSHRCYP2C19SMN1; SMN2BLM
SCHEMBL28563050 0.73 CYP2C19 (0.40) CYP3A4TSHRCYP2C19SMN1; SMN2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112930345-A Novel halo- (3- (phenylsulfonyl) prop-1-ene) pyridine derivatives and uses thereof 韩国科学技术研究院 2021-06-08 CN disclosed