SCHEMBL776644

SCHEMBL776644

Cc1ccc(OP(C)(=O)Oc2ccc(C)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.70
CYP3A4 P08684 1/20 0.70
HPGD P15428 1/20 0.48
ACHE P22303 1/20 0.46
MEN1 O00255 6/20 0.46
KMT2A Q03164 6/20 0.46
LMNA P02545 4/20 0.46
MAPT P10636 1/20 0.46
NPSR1 Q6W5P4 1/20 0.44
HSP90AA1 P07900 1/20 0.43
GAA P10253 1/20 0.43
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11433934 0.91 CYP3A4 (0.59) TSHRCYP3A4HPGDMEN1KMT2A
SCHEMBL5489158 0.85 TSHR (0.70) TSHRCYP3A4HPGDACHEMEN1
SCHEMBL18119755 0.83 CYP3A4 (0.55) TSHRCYP3A4HPGDACHEMEN1
SCHEMBL10336991 0.82 TSHR (1.00) TSHRCYP3A4HPGDACHEMEN1
SCHEMBL27371282 0.82 TSHR (1.00) TSHRCYP3A4HPGDACHEMEN1
SCHEMBL21582 0.82 TSHR (1.00) TSHRCYP3A4HPGDACHEMEN1
SCHEMBL131412 0.82 TSHR (1.00) TSHRCYP3A4HPGDACHEMEN1
SCHEMBL27393883 0.82 TSHR (1.00) TSHRCYP3A4HPGDACHEMEN1
SCHEMBL17350200 0.81 TSHR (0.64) TSHRCYP3A4HPGDACHEMEN1
SCHEMBL28710706 0.81 CYP3A4 (0.64) TSHRCYP3A4HPGDACHEMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3500614-B1 POLYESTER COMPOSITIONS WHICH COMPRISE TETRAMETHYLCYCLOBUTANEDIOL AND ETHYLENE GLYCOL FOR CALENDERING EASTMAN CHEM CO (US) 2025-08-06 EP disclosed
US-12100809-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2024-09-24 US disclosed
CN-111057109-B Benzodioxole derivative with phosphonate and application thereof 西安近代化学研究所 2023-08-11 CN disclosed
US-11447601-B2 Polyester compositions which comprise tetramethylcyclobutanediol and ethylene glycol for calendering EASTMAN CHEMICAL COMPANY (US) 2022-09-20 US disclosed
US-20220149436-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2022-05-12 US disclosed
US-11283107-B2 Non-aqueous liquid electrolyte and non-aqueous liquid electrolyte secondary battery MITSUBISHI CHEMICAL CORPORATION (JP) 2022-03-22 US disclosed
EP-3144064-B1 SELECTIVE HYDROGENATION CATALYST AND METHODS OF MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL CO LP (US) 2021-07-28 EP disclosed
CN-111057109-A Benzodioxane derivative with phosphonate and application thereof 西安近代化学研究所 2020-04-24 CN disclosed
EP-3621141-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2020-03-11 EP disclosed
US-20190229372-A1 NON-AQUEOUS LIQUID ELECTROLYTE AND NON-AQUEOUS LIQUID ELECTROLYTE SECONDARY BATTERY MITSUBISHI CHEMICAL CORPORATION (JP) 2019-07-25 US disclosed
US-20050154114-A1 Compatibilized blends of biodegradable polymers with improved rheology NOVAMONT SPA (IT) 2005-07-14 US disclosed
WO-2005063883-A1 POLYMER BLENDS WITH IMPROVED RHEOLOGY AND IMPROVED UNNOTCHED IMPACT STRENGTH EASTMAN CHEMICAL COMPANY (US) 2005-07-14 WO disclosed
US-20050137332-A1 Polymer blends with improved notched impact strength NOVAMONT SPA (IT) 2005-06-23 US disclosed
US-20050137304-A1 Process for calendering of polyesters STRAND MARC A (US) 2005-06-23 US disclosed
US-20050137356-A1 Polymer blends with improved rheology and improved unnotched impact strength NOVAMONT SPA (IT) 2005-06-23 US disclosed
WO-2005054354-A1 POLYESTER COMPOSITIONS FOR CALENDERING EASTMAN CHEMICAL COMPANY (US) 2005-06-16 WO disclosed
US-20050113556-A1 with a proper balance of inherent viscosity and branching provide superior processing characteristics during calendering EASTMAN CHEMICAL COMPANY 2005-05-26 US disclosed
WO-2004060990-A2 FLAME RETARDANT POLYESTER COMPOSITIONS FOR CALENDERING EASTMAN CHEMICAL COMPANY (US) 2004-07-22 WO disclosed
US-20040127609-A1 Flame retardant polyester compositions for calendering EASTMAN CHEMICAL COMPANY 2004-07-01 US disclosed
US-4377537-A FROM TRIARYL PHOSPHITE AND ALKYL PHOSPHITE OR PHOSPHONOUS ACID DIARYL ESTER AND PHOSPHONOUS ACID DIALKYL ESTER BAYER AKTIENGESELLSCHAFT (DE) 1983-03-22 US disclosed