SCHEMBL28577408

SCHEMBL28577408

Cc1nc(-c2ccc(OCc3cccc(Cl)c3)c(C#N)c2)ncc1C(=O)O

nearest known ligand 0.75

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
XDH P47989 14/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28595695 0.91 XDH (0.81) XDH
SCHEMBL28915921 0.90 XDH (0.76) XDH
SCHEMBL28581167 0.89 XDH (0.75) XDH
SCHEMBL28579205 0.89 XDH (0.75) XDH
SCHEMBL28583625 0.86 XDH (0.80) XDH
SCHEMBL28575362 0.82 XDH (0.81) XDH
SCHEMBL28600147 0.79 XDH (0.71) XDH
SCHEMBL28590015 0.78 XDH (0.69) XDH
SCHEMBL20897567 0.78 MRGPRX4 (0.64) XDH
SCHEMBL28916532 0.77 SMN1; SMN2 (0.58) XDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113004208-A Compound for inhibiting xanthine oxidase activity and preparation method and application thereof 沈阳药科大学 2021-06-22 CN claimed
CN-113004208-A Compound for inhibiting xanthine oxidase activity and preparation method and application thereof 沈阳药科大学 2021-06-22 CN disclosed