Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11306171 | 0.84 | MEN1 (0.66) | MEN1KMT2ALMNAPOLBHSD17B10 | |
| SCHEMBL6169172 | 0.83 | MEN1 (0.83) | MEN1KMT2ALMNAPOLBALDH1A1 | |
| SCHEMBL9524227 | 0.82 | NPC1 (0.56) | MEN1KMT2AALDH1A1HDAC1NPC1 | |
| SCHEMBL11311743 | 0.81 | POLB (0.72) | MEN1KMT2ALMNAPOLBALDH1A1 | |
| SCHEMBL28587098 | 0.80 | LMNA (1.00) | MEN1KMT2ALMNAALDH1A1GAA | |
| SCHEMBL16592515 | 0.79 | GAA (0.59) | MEN1KMT2ALMNAALDH1A1NPC1 | |
| SCHEMBL11309038 | 0.79 | MEN1 (0.60) | MEN1KMT2ALMNAPOLBALDH1A1 | |
| SCHEMBL3102961 | 0.79 | MAPT (0.67) | MEN1KMT2AHSD17B10ALDH1A1HDAC1 | |
| SCHEMBL2070193 | 0.79 | HTT (0.56) | MEN1KMT2ALMNAALDH1A1NPC1 | |
| SCHEMBL29886123 | 0.79 | MAPT (0.67) | MEN1KMT2AHSD17B10ALDH1A1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113061098-B | Amide compound and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-113061098-A | Amide compound and derivative thereof, preparation method, pharmaceutical composition and application | 中国药科大学 | 2021-07-02 | — | — | CN | disclosed |