Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27784732 | 0.98 | LTA4H (0.49) | LTA4HGAAMGAMSIMGAM2 | |
| SCHEMBL22689618 | 0.98 | LTA4H (0.51) | LTA4HGAAMGAMSIMGAM2 | |
| SCHEMBL28210814 | 0.98 | LTA4H (0.51) | LTA4HGAAMGAMSIMGAM2 | |
| SCHEMBL8865384 | 0.98 | LTA4H (0.51) | LTA4HGAAMGAMSIMGAM2 | |
| SCHEMBL1392816 | 0.98 | LTA4H (0.51) | LTA4HGAAMGAMSIMGAM2 | |
| SCHEMBL6037465 | 0.98 | LTA4H (0.51) | LTA4HGAAMGAMSIMGAM2 | |
| Hydrochloric Acid SCHEMBL9054794 | 0.96 | LTA4H (0.50) | LTA4HGAAMGAMSIMGAM2 | |
| Water SCHEMBL8464737 | 0.96 | LTA4H (0.50) | LTA4HGAAMGAMSIMGAM2 | |
| SCHEMBL6074966 | 0.94 | GAA (0.50) | LTA4HGAAMGAMSIMGAM2 | |
| SCHEMBL6821707 | 0.86 | LTA4H (0.49) | LTA4HGAAMGAMSIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2805956-B1 | GAMBOGENIC ACID DERIVATIVES, PREPARATION METHOD AND APPLICATION THEREOF | NINTH PEOPLES HOSPITAL SCHOOL MEDICINE SHANGHAI JIAO TONG UNIV (CN) | 2018-12-26 | — | — | EP | disclosed |
| WO-2018128720-A1 | URACIL CONTAINING COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-07-12 | — | — | WO | disclosed |
| US-9187491-B2 | Gambogenic acid derivatives, preparation method and application thereof | NINTH PEOPLE'S HOSPITAL, SCHOOL MEDICINE SHANGHAI JIAO TONG UNIVERSITY (CN) | 2015-11-17 | — | — | US | disclosed |
| EP-2805956-A1 | GAMBOGENIC ACID DERIVATIVES, PREPARATION METHOD AND APPLICATION THEREOF | Ninth People's Hospital, School Medicine Shanghai Jiao Tong University (CN) | 2014-11-26 | — | — | EP | disclosed |
| WO-2012036546-A1 | CURABLE LIQUID RESIN COMPOSITION FOR OUTERMOST COVERING LAYERS OF OPTICAL FIBER LINE | DSM IP ASSETS B.V. (NL) | 2012-03-22 | — | — | WO | disclosed |
| EP-2428498-A1 | Curable liquid resin composition for outermost covering layers of optical fiber line | DSM IP Assets B.V. (NL) | 2012-03-14 | — | — | EP | disclosed |
| WO-2011100401-A1 | MACROCYCLES AS FACTOR XIA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-08-18 | — | — | WO | disclosed |
| US-7351719-B2 | Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2008-04-01 | — | — | US | disclosed |
| EP-1826200-A2 | Oxime derivative, photopolymerisable composition, colour filter and process for producing the same | FUJIFILM Corporation (JP) | 2007-08-29 | — | — | EP | disclosed |
| US-20040152742-A1 | Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040152742-A1 | Amide compounds having MCH-antagonistic activity and medicaments comprising these compounds | MCHR2, MCHR1, NPY1R | LTA4H 2875/4885GAA 520/4885MGAM 1013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.