Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1D | O15297 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
| ▸ | CTSG | P08311 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20471649 | 0.86 | LMNA (0.36) | PPM1DDPP4LMNACYP2C19HSD17B10 | |
| SCHEMBL25282754 | 0.82 | PPM1D (0.34) | PPM1DDPP4LMNACYP2C19HSD17B10 | |
| SCHEMBL17674517 | 0.82 | PPM1D (0.34) | PPM1DDPP4LMNACYP2C19HSD17B10 | |
| SCHEMBL20471654 | 0.81 | PPM1D (0.34) | PPM1DLMNACYP2C19HSD17B10RAB9A | |
| SCHEMBL23227952 | 0.81 | PPM1D (0.34) | PPM1DLMNACYP2C19HSD17B10RAB9A | |
| SCHEMBL23227860 | 0.81 | PPM1D (0.34) | PPM1DLMNACYP2C19HSD17B10RAB9A | |
| SCHEMBL20471798 | 0.81 | PPM1D (0.34) | PPM1DLMNACYP2C19HSD17B10RAB9A | |
| SCHEMBL18301451 | 0.81 | PPM1D (0.33) | PPM1DLMNACYP2C19HSD17B10RAB9A | |
| SCHEMBL18663540 | 0.81 | PPM1D (0.33) | PPM1DLMNACYP2C19HSD17B10RAB9A | |
| SCHEMBL23227731 | 0.80 | PPM1D (0.33) | PPM1DDPP4LMNACYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107954923-B | Preparation method of key chiral piperidine intermediate of dichroine and halofuginone | 复旦大学 | 2021-07-02 | — | — | CN | disclosed |