Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.50 |
| ▸ | TUBB | P07437 | 1/20 | 0.50 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.50 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.50 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.50 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10590278 | 0.93 | ALDH1A1 (0.72) | KDM4EALDH1A1MAPTGAACYP3A4 | |
| SCHEMBL6704156 | 0.89 | KDM4E (0.59) | KDM4EALDH1A1MAPTGAACYP3A4 | |
| SCHEMBL718719 | 0.89 | ABCG2 (0.61) | KDM4EALDH1A1MAPTGAACYP3A4 | |
| SCHEMBL15513876 | 0.84 | ALDH1A1 (0.67) | KDM4EALDH1A1MAPTGAACYP3A4 | |
| SCHEMBL30049200 | 0.84 | ABCG2 (0.56) | KDM4EALDH1A1MAPTGAACYP3A4 | |
| SCHEMBL27755056 | 0.84 | KDM4E (0.58) | KDM4EALDH1A1MAPTGAACYP3A4 | |
| SCHEMBL29723654 | 0.84 | KDM4E (0.59) | KDM4EALDH1A1MAPTGAAMEN1 | |
| SCHEMBL5137806 | 0.83 | MAPT (0.87) | KDM4EALDH1A1MAPTGAACYP3A4 | |
| Agehoustin A SCHEMBL31237717 | 0.82 | MAPT (0.53) | KDM4EALDH1A1MAPTGAACYP3A4 | |
| SCHEMBL29138747 | 0.80 | KDM4E (0.53) | KDM4EALDH1A1MAPTGAACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112961203-B | Flavonol glycoside derivative and its use and preparation method | 江西中医药大学 | 2021-07-30 | — | — | CN | disclosed |
| CN-112961203-A | Flavonol glycoside derivative and its use and preparation method | 江西中医药大学 | 2021-06-15 | — | — | CN | disclosed |