Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.72 |
| ▸ | CNR1 | P21554 | 3/20 | 0.59 |
| ▸ | CNR2 | P34972 | 3/20 | 0.59 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.54 |
| ▸ | TUBB | P07437 | 1/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.54 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.54 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.54 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.54 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28577420 | 0.92 | SLC22A12 (0.72) | SLC22A12CNR1CNR2LMNAL3MBTL1 | |
| SCHEMBL28584067 | 0.88 | CNR2 (0.59) | SLC22A12CNR1CNR2TUBB4ATUBB | |
| SCHEMBL28579237 | 0.88 | SLC22A12 (0.68) | SLC22A12CNR1CNR2LMNAL3MBTL1 | |
| SCHEMBL28589801 | 0.88 | SLC22A12 (0.67) | SLC22A12CNR1CNR2TUBB4ATUBB | |
| SCHEMBL28584701 | 0.87 | SLC22A12 (0.66) | SLC22A12CNR1CNR2LMNAL3MBTL1 | |
| SCHEMBL28589812 | 0.87 | SLC22A12 (0.66) | SLC22A12CNR1CNR2LMNAL3MBTL1 | |
| SCHEMBL28914924 | 0.87 | SLC22A12 (0.66) | SLC22A12CNR2LMNANPSR1CYP1A2 | |
| SCHEMBL28595188 | 0.85 | SLC22A12 (0.80) | SLC22A12CNR1CNR2LMNAL3MBTL1 | |
| SCHEMBL28575852 | 0.84 | SLC22A12 (0.62) | SLC22A12CNR1CNR2LMNAL3MBTL1 | |
| SCHEMBL28589808 | 0.83 | SLC22A12 (1.00) | SLC22A12CNR1CNR2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004188-B | Indole derivative, preparation method and application | 沈阳药科大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-113004188-A | Indole derivative, preparation method and application | 沈阳药科大学 | 2021-06-22 | — | — | CN | disclosed |