Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28571008 | 0.90 | L3MBTL1 (0.52) | SLC22A12L3MBTL1MAPK1NR1H4HDAC1 | |
| SCHEMBL28577420 | 0.89 | SLC22A12 (0.72) | SLC22A12L3MBTL1MAPK1LMNAHDAC1 | |
| SCHEMBL28589812 | 0.88 | SLC22A12 (0.66) | SLC22A12L3MBTL1MAPK1LMNAHDAC1 | |
| SCHEMBL28589801 | 0.87 | SLC22A12 (0.67) | SLC22A12L3MBTL1LMNACNR2CNR1 | |
| SCHEMBL4359539 | 0.87 | L3MBTL1 (0.70) | L3MBTL1MAPK1LMNACNR2CNR1 | |
| SCHEMBL28584701 | 0.86 | SLC22A12 (0.66) | SLC22A12L3MBTL1MAPK1LMNAHDAC1 | |
| SCHEMBL28914924 | 0.86 | SLC22A12 (0.66) | SLC22A12MAPK1LMNACNR2CHRM1 | |
| SCHEMBL28584442 | 0.85 | CHRM1 (0.68) | SLC22A12L3MBTL1LMNACNR2CNR1 | |
| SCHEMBL28577804 | 0.84 | SLC22A12 (0.72) | SLC22A12L3MBTL1MAPK1LMNAHDAC1 | |
| SCHEMBL28584112 | 0.81 | SLC22A12 (0.58) | SLC22A12L3MBTL1MAPK1LMNACNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004188-B | Indole derivative, preparation method and application | 沈阳药科大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-113004188-A | Indole derivative, preparation method and application | 沈阳药科大学 | 2021-06-22 | — | — | CN | disclosed |