Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 14/20 | 0.53 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.52 |
| ▸ | LIPC | P11150 | 1/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28577831 | 1.00 | FFAR4 (0.53) | FFAR4LIPGLIPCNOTUMEPHX2 | |
| SCHEMBL28584607 | 1.00 | FFAR4 (0.53) | FFAR4LIPGLIPCNOTUMEPHX2 | |
| SCHEMBL23631982 | 0.93 | LIPG (0.59) | FFAR4LIPGLIPCNOTUMEPHX2 | |
| SCHEMBL23632266 | 0.93 | LIPG (0.59) | FFAR4LIPGLIPCNOTUMEPHX2 | |
| SCHEMBL23631980 | 0.93 | LIPG (0.59) | FFAR4LIPGLIPCNOTUMEPHX2 | |
| SCHEMBL23632079 | 0.88 | LIPG (0.56) | FFAR4LIPGLIPCNOTUMEPHX2 | |
| SCHEMBL2089459 | 0.81 | LIPG (0.45) | FFAR4LIPGLIPCNOTUM | |
| SCHEMBL30065058 | 0.81 | ACACB (0.53) | LIPGLIPCNOTUM | |
| SCHEMBL30065043 | 0.81 | ACACB (0.53) | LIPGLIPCNOTUM | |
| SCHEMBL21616648 | 0.80 | NOTUM (0.54) | FFAR4NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072521-B | ROR gamma t inhibitor and application thereof in medicines | 广东东阳光药业股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-113072521-A | ROR gamma t inhibitor and application thereof in medicine | 广东东阳光药业有限公司 | 2021-07-06 | — | — | CN | disclosed |