SCHEMBL28577983

SCHEMBL28577983

O=C(O)c1cc(C(=O)O)cc(C2=CCC(C(=O)O)(c3ccccc3)C=C2)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 3/20 0.37
KMO O15229 1/20 0.34
AKR1C1 Q04828 1/20 0.31
KDM4E B2RXH2 2/20 0.31
MAPT P10636 2/20 0.31
ALDH1A1 P00352 2/20 0.31
DAO P14920 1/20 0.31
TSHR P16473 1/20 0.31
NAPRT Q6XQN6 1/20 0.31
POLB P06746 1/20 0.31
BLM P54132 1/20 0.31
GRM1 Q13255 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
MEN1 O00255 1/20 0.31
MAPK1 P28482 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31
HDAC4 P56524 2/20 0.30
TP53 P04637 1/20 0.30
IP6K1 Q92551 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9199935 0.88 EGFR (0.36) ALDH1A1DAOTSHRNAPRTTDP1
SCHEMBL27042598 0.86 HDAC4 (0.37) AKR1C1TDP1MEN1KMT2AHDAC4
SCHEMBL30159269 0.85 RARA (0.37) ALDH1A1DAOTSHRNAPRTTDP1
SCHEMBL22325605 0.81 POLB (0.32) AKR1C1POLBHDAC4
SCHEMBL27036929 0.81 POLB (0.32) AKR1C1POLBHDAC4
SCHEMBL2521627 0.75 AKR1C1 (0.37) AKR1C1MAPTALDH1A1BLMKMT2A
SCHEMBL30589358 0.74 GAA (0.36) MAPTDAOTSHRNAPRTTDP1
SCHEMBL18259088 0.74 NPC1 (0.38) IP6K1IP6K3IP6K2
SCHEMBL347447 0.73 AKR1C1 (0.38) AKR1C1HDAC4
SCHEMBL30661188 0.73 MEN1 (0.38) MAPTALDH1A1POLBMEN1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108929442-B Metal organic compound based on rigid triacid ligand p-terphenyl-3, 4', 5-tricarboxylic acid and preparation method and application thereof 天津师范大学 2021-06-18 CN claimed
CN-113588760-B Method for detecting nitrite ions through ratio type electrochemistry 江苏大学 2023-06-13 CN disclosed
CN-113588760-A Method for detecting nitrite ions through ratio type electrochemistry 江苏大学 2021-11-02 CN disclosed
CN-108929442-B Metal organic compound based on rigid triacid ligand p-terphenyl-3, 4', 5-tricarboxylic acid and preparation method and application thereof 天津师范大学 2021-06-18 CN disclosed
CN-108929442-B Metal organic compound based on rigid triacid ligand p-terphenyl-3, 4', 5-tricarboxylic acid and preparation method and application thereof 天津师范大学 2021-06-18 CN disclosed
CN-108929442-B Metal organic compound based on rigid triacid ligand p-terphenyl-3, 4', 5-tricarboxylic acid and preparation method and application thereof 天津师范大学 2021-06-18 CN disclosed
CN-108931505-B Method for detecting nitrite ions based on rare earth metal organic framework material 天津师范大学 2021-05-14 CN disclosed
CN-108931505-B Method for detecting nitrite ions based on rare earth metal organic framework material 天津师范大学 2021-05-14 CN disclosed