Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19410867 | 0.94 | HPGD (0.50) | HPGDGPR119RECQLEPHX1EPHX2 | |
| SCHEMBL30493418 | 0.91 | HPGD (0.43) | HPGDGPR119RECQLEPHX1HRH3 | |
| SCHEMBL2926865 | 0.89 | HPGD (0.51) | HPGDGPR119RECQLEPHX1EPHX2 | |
| SCHEMBL396843 | 0.83 | EPHX1 (0.49) | HPGDGPR119RECQLEPHX1EPHX2 | |
| SCHEMBL31170608 | 0.82 | HPGD (0.47) | HPGDGPR119RECQLEPHX1EPHX2 | |
| SCHEMBL4609802 | 0.82 | EPHX1 (0.51) | HPGDGPR119RECQLEPHX1EPHX2 | |
| SCHEMBL27388627 | 0.78 | USP2 (0.62) | HPGDRECQLEPHX1HRH3EPHX2 | |
| SCHEMBL28577405 | 0.77 | HPGD (0.54) | HPGDGPR119RECQLEPHX1HRH3 | |
| SCHEMBL25271054 | 0.77 | HPGD (0.44) | HPGDGPR119RECQLEPHX1EPHX2 | |
| SCHEMBL31567046 | 0.77 | HPGD (0.41) | HPGDGPR119RECQLEPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112778299-A | Piperazine ureido derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2021-05-11 | — | — | CN | disclosed |