Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 14/20 | 0.44 |
| ▸ | SMYD3 | Q9H7B4 | 4/20 | 0.44 |
| ▸ | F2 | P00734 | 4/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28580156 | 1.00 | F10 (0.44) | F10SMYD3F2PRSS1PRSS2 | |
| SCHEMBL28572149 | 0.91 | F10 (0.45) | F10SMYD3F2PRSS1PRSS2 | |
| SCHEMBL28572148 | 0.91 | F10 (0.45) | F10SMYD3F2PRSS1PRSS2 | |
| SCHEMBL25016089 | 0.89 | F10 (0.52) | F10SMYD3F2PRSS1PRSS2 | |
| SCHEMBL28588635 | 0.88 | SMYD3 (0.47) | F10SMYD3F2PRSS1PRSS2 | |
| SCHEMBL28588633 | 0.88 | SMYD3 (0.47) | F10SMYD3F2PRSS1PRSS2 | |
| SCHEMBL31689670 | 0.87 | F10 (0.45) | F10SMYD3F2PRSS1PRSS2 | |
| SCHEMBL31689686 | 0.87 | SMYD3 (0.46) | F10SMYD3F2PRSS1PRSS2 | |
| SCHEMBL25017655 | 0.85 | F10 (0.43) | F10SMYD3F2DRD4 | |
| SCHEMBL28578356 | 0.85 | F10 (0.43) | F10SMYD3F2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112996529-A | Matriptase 2 inhibitor and application thereof | 迪斯克医药公司 | 2021-06-18 | — | — | CN | disclosed |