Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1D | O15297 | 2/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL924412 | 1.00 | PPM1D (0.34) | PPM1DHCRTR1HCRTR2POLBL3MBTL1 | |
| SCHEMBL2699159 | 0.89 | PPM1D (0.33) | PPM1D | |
| SCHEMBL29245844 | 0.87 | PPM1D (0.34) | PPM1D | |
| SCHEMBL376587 | 0.87 | PPM1D (0.34) | PPM1D | |
| SCHEMBL3525995 | 0.87 | PPM1D (0.34) | PPM1D | |
| SCHEMBL5314317 | 0.87 | PPM1D (0.34) | PPM1D | |
| SCHEMBL3470472 | 0.87 | PPM1D (0.34) | PPM1D | |
| SCHEMBL30729563 | 0.87 | PPM1D (0.34) | PPM1D | |
| SCHEMBL2634064 | 0.87 | PPM1D (0.34) | PPM1D | |
| SCHEMBL30842585 | 0.85 | NR1H2 (0.38) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113072521-A | ROR gamma t inhibitor and application thereof in medicine | 广东东阳光药业有限公司 | 2021-07-06 | — | — | CN | disclosed |