Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29245844 | 1.00 | PPM1D (0.34) | PPM1DNR1H2 | |
| SCHEMBL376587 | 1.00 | PPM1D (0.34) | PPM1DNR1H2 | |
| SCHEMBL3525995 | 1.00 | PPM1D (0.34) | PPM1DNR1H2 | |
| SCHEMBL5314317 | 1.00 | PPM1D (0.34) | PPM1DNR1H2 | |
| SCHEMBL2634064 | 1.00 | PPM1D (0.34) | PPM1DNR1H2 | |
| SCHEMBL3470472 | 1.00 | PPM1D (0.34) | PPM1DNR1H2 | |
| SCHEMBL924412 | 0.87 | PPM1D (0.34) | PPM1D | |
| SCHEMBL4725652 | 0.87 | BDKRB2 (0.34) | PPM1D | |
| SCHEMBL28580288 | 0.87 | PPM1D (0.34) | PPM1D | |
| SCHEMBL4416435 | 0.86 | PPM1D (0.33) | PPM1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220532-A1 | PYRROLIDINE KRAS INHIBITORS | INCYTE CORPORATION (US) | 2024-10-24 | — | — | WO | disclosed |
| WO-2024015731-A1 | FUSED TRICYCLIC COMPOUNDS AS INHIBITORS OF KRAS G12V MUTANTS | INCYTE CORPORATION (US) | 2024-01-18 | — | — | WO | disclosed |