SCHEMBL2858065

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5372624	0.89	SMN1; SMN2 (0.60)	SMN1; SMN2NPY5RDYRK1ACLK2CLK3
	SCHEMBL2870409	0.82	JAK2 (0.56)	DYRK1ACLK2ROCK1LRRK2KDM4E
	SCHEMBL27558704	0.80	TTK (0.56)	LRRK2NTRK1TTKPDPK1AURKA
	SCHEMBL1663544	0.78	CLK2 (0.54)	SMN1; SMN2DYRK1ACLK2CLK3LRRK2
	SCHEMBL13811362	0.78	NTRK1 (0.46)	DYRK1ACLK2CLK3LRRK2NTRK1
	SCHEMBL20237020	0.78	SMN1; SMN2 (0.68)	SMN1; SMN2NPY5RNPC1RAB9AALDH1A1
	SCHEMBL13742747	0.75	AURKA (0.56)	NTRK1TTKPDPK1AURKA
	SCHEMBL2859988	0.75	ITK (0.57)	DYRK1ACLK2CLK3LRRK2NTRK1
	SCHEMBL2862072	0.74	DYRK1A (0.59)	DYRK1A
	SCHEMBL2858874	0.74	NPC1 (0.61)	SMN1; SMN2NPC1RAB9ANTRK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.