SCHEMBL2859988

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27558704	0.83	TTK (0.56)	TTKAURKBPLK4CHEK2CYP3A4
	SCHEMBL5380958	0.82	AURKA (0.58)	ITKTTKAURKBPLK4CHEK2
	SCHEMBL5783999	0.81	AURKA (0.57)	ITKTTKAURKBPLK4CHEK2
	SCHEMBL2870906	0.79	TTK (0.72)	TTKAURKBNTRK1AURKACLK2
	SCHEMBL13742747	0.78	AURKA (0.56)	ITKTTKAURKBNTRK1AURKA
	SCHEMBL5386918	0.78	TTK (0.56)	ITKTTKAURKBPLK4CHEK2
	SCHEMBL2861637	0.77	PDPK1 (0.59)	ITKNTRK1AURKACLK2DYRK1A
	SCHEMBL2861303	0.76	TTK (0.75)	TTKAURKBNTRK1AURKA
	SCHEMBL2869839	0.76	MAP2K4 (0.61)	ITKTTKAURKBPLK4NTRK1
	SCHEMBL13480551	0.75	KMT2A (0.62)	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.