Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.46 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28603226 | 0.93 | TLR9 (0.47) | PDE10ATLR9TLR8TLR7EGFR | |
| SCHEMBL1551553 | 0.90 | PDE10A (0.43) | PDE10ATLR9TLR8TLR7EGFR | |
| SCHEMBL14960278 | 0.89 | MEN1 (0.42) | PDE10ATLR9TLR8TLR7EGFR | |
| SCHEMBL1550581 | 0.88 | MEN1 (0.44) | PDE10ATLR9TLR8TLR7NOS2 | |
| SCHEMBL27832688 | 0.84 | TLR9 (0.45) | PDE10ATLR9TLR8TLR7EGFR | |
| SCHEMBL9971272 | 0.77 | PDE10A (0.77) | PDE10AKMT2AMEN1SMN1; SMN2KDM4E | |
| SCHEMBL23759740 | 0.76 | KDM4E (0.55) | TLR8TLR7EGFRNOS3NOS1 | |
| SCHEMBL28580709 | 0.76 | PDE10A (0.53) | PDE10AKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL28500268 | 0.74 | TLR9 (0.42) | PDE10ATLR9EGFRKMT2AMEN1 | |
| SCHEMBL28603449 | 0.74 | KDM4E (0.52) | KMT2ALMNASMN1; SMN2HTTMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113087674-B | Method for synthesizing quinoxaline compound under catalysis of visible light induced photosensitizer | 河南大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-113087674-A | Method for synthesizing quinoxaline compound under visible light induced iron catalysis condition | 河南大学 | 2021-07-09 | — | — | CN | disclosed |