Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28594904 | 0.90 | PDE10A (0.50) | PDE10AKDM4ENQO2GPBAR1CYSLTR1 | |
| SCHEMBL9971272 | 0.83 | PDE10A (0.77) | PDE10AKDM4ECYP1A2MEN1MAPT | |
| SCHEMBL28587839 | 0.80 | PDE10A (0.41) | PDE10AKDM4ECYP1A2MAPTALDH1A1 | |
| SCHEMBL29639030 | 0.80 | PDE10A (0.41) | PDE10AKDM4ECYP1A2MAPTALDH1A1 | |
| SCHEMBL6436852 | 0.76 | KDM4E (0.44) | PDE10AKDM4ENQO2GPBAR1CYSLTR1 | |
| SCHEMBL28580708 | 0.76 | PDE10A (0.46) | PDE10AKDM4EMEN1MAPTKMT2A | |
| SCHEMBL28603226 | 0.76 | TLR9 (0.47) | PDE10AKDM4EMEN1MAPTKMT2A | |
| SCHEMBL6114924 | 0.76 | ATM (0.57) | PDE10AKDM4ECYP1A2ALDH1A1GAA | |
| SCHEMBL28165727 | 0.75 | PDE10A (0.44) | PDE10AKDM4ENQO2CYSLTR1CYP1A2 | |
| SCHEMBL7068584 | 0.73 | PDE10A (0.71) | PDE10AKDM4ECYP1A2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113087674-B | Method for synthesizing quinoxaline compound under catalysis of visible light induced photosensitizer | 河南大学 | 2022-06-17 | — | — | CN | disclosed |
| CN-113087674-A | Method for synthesizing quinoxaline compound under visible light induced iron catalysis condition | 河南大学 | 2021-07-09 | — | — | CN | disclosed |