SCHEMBL28580835

SCHEMBL28580835

CC/C(C=O)=C\NCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.53
ADH1C P00326 1/20 0.53
ADH1A P07327 1/20 0.53
ADH7 P40394 1/20 0.53
CYP2C9 P11712 1/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
ALDH1A1 P00352 4/20 0.41
MAPT P10636 2/20 0.41
NPC1 O15118 1/20 0.41
HPGD P15428 1/20 0.41
RAB9A P51151 1/20 0.41
KMT2A Q03164 2/20 0.41
IDO1 P14902 2/20 0.39
THRB P10828 1/20 0.39
MEN1 O00255 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
RIPK1 Q13546 1/20 0.39
NR4A1 P22736 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23620721 0.79 ADH1B (0.48) ADH1BADH1CADH1AADH7CYP2C9
SCHEMBL28153270 0.79 ADH1B (0.57) ADH1BADH1CADH1AADH7CYP2C9
SCHEMBL28471030 0.78 ADH1B (0.50) ADH1BADH1CADH1AADH7CYP2C9
SCHEMBL26983698 0.75 CYP2C9 (0.60) ADH1BADH1CADH1AADH7CYP2C9
SCHEMBL23188929 0.75 ADH1B (0.57) ADH1BADH1CADH1AADH7CYP2C9
SCHEMBL627479 0.74 ADH1B (0.54) ADH1BADH1CADH1AADH7CYP2C9
SCHEMBL10151057 0.72 ADH1B (0.53) ADH1BADH1CADH1AADH7CYP2C9
SCHEMBL14754423 0.72 ADH1B (0.49) ADH1BADH1CADH1AADH7CYP2C9
SCHEMBL7449229 0.71 ADH1B (0.52) ADH1BADH1CADH1AADH7CYP2C9
SCHEMBL7449222 0.71 ADH1B (0.52) ADH1BADH1CADH1AADH7CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109232284-B Polysubstituted enamine aldehyde derivative and preparation method thereof 华侨大学 2021-05-11 CN disclosed