SCHEMBL28580900

SCHEMBL28580900

Brc1ccc(C2CCC(C3CC3)CC2)cc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 5/20 0.43
KCNH2 Q12809 2/20 0.43
MAOB P27338 2/20 0.43
RCOR1 Q9UKL0 2/20 0.43
KDM1B Q8NB78 1/20 0.43
ESR2 Q92731 3/20 0.41
BRD4 O60885 1/20 0.41
CYP2A6 P11509 1/20 0.40
POLB P06746 1/20 0.39
HTR2C P28335 1/20 0.38
HTR2B P41595 1/20 0.38
ESR1 P03372 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
SLC6A3 Q01959 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL265495 0.92 KDM1A (0.48) KDM1AKCNH2MAOBRCOR1KDM1B
SCHEMBL14804315 0.92 KDM1A (0.48) KDM1AKCNH2MAOBRCOR1KDM1B
SCHEMBL9184183 0.89 KDM1A (0.36) KDM1AKCNH2MAOBRCOR1KDM1B
SCHEMBL10743509 0.89 ESR2 (0.57) KDM1AKCNH2MAOBRCOR1KDM1B
SCHEMBL10743505 0.89 ESR2 (0.57) KDM1AKCNH2MAOBRCOR1KDM1B
SCHEMBL9184185 0.89 KDM1A (0.36) KDM1AKCNH2MAOBRCOR1KDM1B
Hydrochloric Acid SCHEMBL5060582 0.87 KDM1A (0.48) KDM1AKCNH2MAOBRCOR1KDM1B
Methyl Alcohol SCHEMBL27656751 0.85 ESR2 (0.50) KDM1AKCNH2MAOBRCOR1KDM1B
Cyanide SCHEMBL27694948 0.85 KDM1A (0.43) KDM1AKCNH2MAOBRCOR1KDM1B
SCHEMBL10743018 0.84 ALDH1A1 (0.49) KDM1ARCOR1ESR2BRD4ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112980457-A Liquid crystal compound, liquid crystal composition, liquid crystal display element, or liquid crystal display 石家庄诚志永华显示材料有限公司 2021-06-18 CN disclosed