Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16919433 | 0.97 | L3MBTL1 (0.50) | ATML3MBTL1KDM4EHDAC4ALDH1A1 | |
| SCHEMBL16409596 | 0.91 | ATM (0.57) | ATML3MBTL1KDM4EHDAC4ALDH1A1 | |
| SCHEMBL16409611 | 0.91 | ATM (0.57) | ATML3MBTL1KDM4EHDAC4ALDH1A1 | |
| SCHEMBL26750950 | 0.90 | ATM (0.55) | ATML3MBTL1KDM4EHDAC4ALDH1A1 | |
| SCHEMBL16409583 | 0.90 | ATM (0.55) | ATML3MBTL1KDM4EHDAC4ALDH1A1 | |
| SCHEMBL16593138 | 0.90 | L3MBTL1 (0.60) | ATML3MBTL1KDM4EHDAC4ALDH1A1 | |
| SCHEMBL17038449 | 0.90 | ATM (0.55) | ATML3MBTL1KDM4EHDAC4ALDH1A1 | |
| SCHEMBL15458632 | 0.89 | ATM (0.47) | ATML3MBTL1KDM4EHDAC4ALDH1A1 | |
| SCHEMBL15458652 | 0.89 | ATM (0.47) | ATML3MBTL1KDM4EHDAC4ALDH1A1 | |
| SCHEMBL26622420 | 0.89 | L3MBTL1 (0.47) | ATML3MBTL1KDM4EHDAC4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232381-B | 9- ([1,1' -biphenyl ] -3-yl) -2' -bromo-2, 9' -bicarbazole and synthesis method thereof | 河南省科学院化学研究所有限公司 | 2021-06-11 | — | — | CN | claimed |
| CN-109232381-B | 9- ([1,1' -biphenyl ] -3-yl) -2' -bromo-2, 9' -bicarbazole and synthesis method thereof | 河南省科学院化学研究所有限公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-109232381-B | 9- ([1,1' -biphenyl ] -3-yl) -2' -bromo-2, 9' -bicarbazole and synthesis method thereof | 河南省科学院化学研究所有限公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-109232381-B | 9- ([1,1' -biphenyl ] -3-yl) -2' -bromo-2, 9' -bicarbazole and synthesis method thereof | 河南省科学院化学研究所有限公司 | 2021-06-11 | — | — | CN | disclosed |