Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.73 |
| ▸ | MAPT | P10636 | 5/20 | 0.73 |
| ▸ | HTT | P42858 | 2/20 | 0.73 |
| ▸ | THRB | P10828 | 1/20 | 0.73 |
| ▸ | CLK2 | P49760 | 2/20 | 0.64 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.64 |
| ▸ | PRKX | P51817 | 1/20 | 0.64 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.64 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.64 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.60 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28573140 | 0.87 | KDM4E (0.71) | ALDH1A1MAPTHTTCLK2CLK4 | |
| SCHEMBL28569399 | 0.85 | MAP4K4 (0.69) | ALDH1A1MAPTHTTTHRBCLK2 | |
| SCHEMBL28573658 | 0.84 | MAOB (0.73) | ALDH1A1MAPTHTTTHRBCLK2 | |
| SCHEMBL28570043 | 0.82 | PRKX (0.55) | ALDH1A1MAPTHTTTHRBCLK2 | |
| SCHEMBL28569383 | 0.82 | KDM4E (0.61) | ALDH1A1MAPTHTTCLK2CLK4 | |
| SCHEMBL4578714 | 0.81 | CLK2 (0.65) | ALDH1A1MAPTHTTTHRBCLK2 | |
| SCHEMBL5141417 | 0.79 | MEN1 (0.71) | ALDH1A1MAPTHTTHPGDMEN1 | |
| SCHEMBL23084047 | 0.79 | HPGD (0.63) | ALDH1A1MAPTCLK2CLK4PRKX | |
| SCHEMBL25298408 | 0.78 | MMP1 (0.61) | ALDH1A1MAPTHTTTHRBCLK2 | |
| SCHEMBL25247202 | 0.78 | MMP1 (0.61) | ALDH1A1MAPTHTTTHRBCLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109942544-B | Novel indazole derivative kinase inhibitor | 中国科学院合肥物质科学研究院 | 2021-06-11 | — | — | CN | disclosed |