Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | DUT | P33316 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28693496 | 0.99 | ALDH1A1 (0.56) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL12634929 | 0.93 | ALDH1A1 (0.64) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL31367158 | 0.93 | ALDH1A1 (0.64) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL25386609 | 0.89 | ALDH1A1 (0.58) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL17558097 | 0.81 | TUBB1 (0.43) | ALDH1A1HPGDHTTSMN1; SMN2MAPT | |
| SCHEMBL29398599 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL22843772 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL8372730 | 0.80 | ALDH1A1 (0.87) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL17558155 | 0.80 | BACE1 (0.37) | ALDH1A1PTGDR2KMT2AMEN1MAPT | |
| SCHEMBL1805185 | 0.80 | NPC1 (0.38) | ALDH1A1HPGDHTTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107879960-B | Lipids and lipid compositions for delivery of active ingredients | 诺华股份有限公司 | 2021-06-22 | — | — | CN | disclosed |