Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.37 |
| ▸ | FDPS | P14324 | 9/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11151119 | 1.00 | DNM1 (0.44) | DNM1TSHRTHRBGGPS1FDPS | |
| SCHEMBL9400789 | 0.97 | TSHR (0.42) | DNM1TSHRTHRBGGPS1FDPS | |
| SCHEMBL679280 | 0.97 | TSHR (0.42) | DNM1TSHRTHRBGGPS1FDPS | |
| SCHEMBL9175197 | 0.97 | TSHR (0.42) | DNM1TSHRTHRBGGPS1FDPS | |
| Hydrochloric Acid SCHEMBL8586216 | 0.95 | DNM1 (0.44) | DNM1TSHRTHRBGGPS1FDPS | |
| Hydrochloric Acid SCHEMBL28405000 | 0.95 | DNM1 (0.44) | DNM1TSHRTHRBGGPS1FDPS | |
| SCHEMBL16860019 | 0.95 | DNM1 (0.40) | DNM1TSHRTHRBGGPS1FDPS | |
| SCHEMBL5268953 | 0.95 | DNM1 (0.38) | DNM1TSHRTHRBGGPS1FDPS | |
| Isothiocyanate SCHEMBL29243219 | 0.82 | GGPS1 (0.32) | DNM1GGPS1 | |
| SCHEMBL21461241 | 0.79 | TSHR (0.44) | DNM1TSHRTHRBGGPS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113046796-A | Preparation method of nano double crystal layer and nano double crystal layer | 铂识科技股份有限公司 | 2021-06-29 | — | — | CN | disclosed |