Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.47 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854924 | 0.88 | RARB (0.55) | PTPN11PTPROFFAR1FFAR4HDAC3 | |
| SCHEMBL2855523 | 0.85 | PTPN11 (0.43) | PTPN11PTPROFFAR1FFAR4ALDH1A1 | |
| SCHEMBL2861907 | 0.84 | PDE6D (0.48) | PTPN11PTPROFFAR1FFAR4HDAC3 | |
| SCHEMBL1734728 | 0.83 | LTB4R2 (0.53) | PTPN11PTPROFFAR1FFAR4LTB4R2 | |
| SCHEMBL2853695 | 0.83 | PTPN11 (0.40) | PTPN11PTPROFFAR1FFAR4ALDH1A1 | |
| SCHEMBL1734774 | 0.82 | PTPN11 (0.66) | PTPN11PTPROFFAR1FFAR4LTB4R2 | |
| SCHEMBL2853426 | 0.76 | LTB4R2 (0.61) | PTPN11PTPROLTB4R2ALDH1A1 | |
| SCHEMBL13711743 | 0.75 | RARB (0.71) | HDAC3HDAC1HDAC2HDAC6NCOR2 | |
| SCHEMBL4398063 | 0.74 | LTB4R2 (0.64) | HDAC3HDAC1HDAC2HDAC6NCOR2 | |
| SCHEMBL2857121 | 0.74 | S1PR1 (0.45) | FFAR1FFAR4ALDH1A1PLK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654247-B1 | ALKYNYL ARYL CARBOXAMIDES | MERCK SERONO SA (CH) | 2010-01-20 | — | — | EP | claimed |